
Polynucleotides
Polynucleotide treatments are advanced regenerative injectables designed to repair, rejuvenate, and strengthen the skin from within. Derived from highly purified DNA fragments, they work by stimulating cellular repair, improving hydration, and boosting collagen production for healthier, smoother, and more resilient skin.
At our private aesthetics clinic in the Cotswolds, we offer a range of leading polynucleotide treatments tailored to different skin concerns, including delicate under-eye rejuvenation, full-face skin quality improvement, and targeted repair for ageing or damaged skin.
Polynucleotide Treatments We Offer
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Vitaran Eye
Specifically designed for the delicate under-eye area to improve dark circles, fine lines, and crepey skin. -
Vitaran I
Ideal for overall skin rejuvenation, hydration, and improving skin texture. -
Vitaran II
A more intensive formulation for advanced skin regeneration and ageing concerns. -
Plinest
Supports skin repair, elasticity, and hydration for improved overall skin quality. -
Plinest Eye
Designed to treat fine lines, crepey texture, and tired-looking eyes. -
Rejuran S
Targeted treatment for acne scarring and more advanced skin damage. -
Rejuran I
Focused on improving overall skin quality, hydration, and elasticity. -
Rejuran Healer
A full-face rejuvenation treatment designed to restore radiance, smoothness, and youthful skin quality. -
Rejuran Hydro Boost
Combines deep hydration with regenerative benefits for dry, dull, or ageing skin.
What Polynucleotides Can Improve
Polynucleotide treatments are ideal for:
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Fine lines and wrinkles
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Dull or dehydrated skin
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Loss of elasticity
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Under-eye ageing and dark circles
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Acne scarring and skin damage
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Overall skin quality and regeneration
What to Expect
After a detailed consultation, the most suitable polynucleotide treatment will be selected for your skin concerns. Treatments involve small injections into the skin and are typically quick with minimal downtime.
Mild redness, swelling, or small injection marks may occur but usually settle within 24–48 hours.
Results & Longevity
Results develop gradually as the skin repairs and regenerates from within. Improvements in texture, hydration, and radiance become more noticeable over several weeks. A course of treatments is usually recommended for optimal results.
FAQs
What are polynucleotides used for?
They are used to repair and regenerate the skin, improving hydration, texture, elasticity, and overall skin quality.
Are polynucleotides the same as fillers?
No. They do not add volume or change facial shape. They work by improving skin health at a cellular level.
How many treatments will I need?
A course of treatments is usually recommended depending on your skin concerns and the product used.
When will I see results?
Initial improvements may be seen within a few weeks, with continued improvement over time as skin regenerates.
Is there any downtime?
Downtime is minimal. Mild redness or swelling may occur but typically resolves within 1–2 days.
Can polynucleotides be combined with other treatments?
Yes. They are often combined with skin boosters, Botox, or other aesthetic treatments as part of a bespoke plan.


